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. Author manuscript; available in PMC: 2022 Apr 6.
Published in final edited form as: Nature. 2019 Aug 15;572(7770):467–473. doi: 10.1038/s41586-019-1492-9

Figure 5. Integrin-dependent adhesion underlies posterior endoderm movement and MyoII activation during wave propagation:

Figure 5.

(a) Still of the apical side of cells during MyoII propagation. White arrow: cell attachment to the vitelline membrane. The plasma membrane is labelled with Gap43. N=4 embryos. (b) Schematic of scab expression in the embryo. (c-d) Time-lapse of a control (water injected) (c) and a scab RNAi embryo (d). The yellow arrows are proportional to the velocities of cells in the propagation region. Two representative cells are marked in yellow. N=4 embryos each. (e-f) Kymograph heat-maps of MyoII integrated intensity and cell velocities in control (e) and scab RNAi (f) injected embryos. Dashed line: boundary between primordium and propagation regions. N=622 cells from 4 water and 693 cells from 4 scab RNAi injected embryos.