Table 3.
Risk factors for lymph node metastasis
| Univariable analysis | Multivariable analysis | |||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| Odds ratio | 95% CI | p value | Odds ratio | 95% CI | p value | |
| Age | ||||||
| ≥40 years | Reference | |||||
| <40 years | 1.32 | 1.05~1.65 | 0.017 | 1.4 | 1.03~1.89 | 0.031 |
| Gender | ||||||
| Male | Reference | |||||
| Female | 1.15 | 1.01~1.31 | 0.033 | 1.15 | 0.97~1.37 | 0.867 |
| Tumor size | ||||||
| <2 cm | Reference | |||||
| ≥2 cm | 10.19 | 7.89~13.18 | <0.001 | 3.01 | 2.28~3.99 | <0.001 |
| pT-stage | ||||||
| T1 | Reference | |||||
| T2 | 6.02 | 4.90~7.40 | <0.001 | 4.99 | 4.02~6.18 | <0.001 |
| T3 | 17.59 | 14.38~21.52 | <0.001 | 13.42 | 10.85~16.61 | <0.001 |
| T4 | 73.51 | 53.18~101.60 | <0.001 | 50.84 | 36.3~71.22 | <0.001 |
| Tumor location | ||||||
| Distal | Reference | |||||
| Middle | 1.14 | 0.98~1.34 | 0.087 | 0.79 | 0.65~0.97 | 0.024 |
| Upper | 1.91 | 1.62~2.24 | <0.001 | 0.88 | 0.71~1.10 | 0.263 |
| Diffuse | 22.15 | 11.09~44.24 | <0.001 | 2.01 | 0.90~4.47 | 0.089 |
| Histology | ||||||
| Intestinal | Reference | |||||
| Diffuse & mixed | 2.06 | 1.81~2.33 | <0.001 | 1.25 | 1.06~1.49 | 0.010 |