Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 23;9:846782. doi: 10.3389/fmed.2022.846782

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Ladha, Caspers, Willermain and de Smet.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Surgical approaches for subretinal delivery. Intravitreal injection (A), subretinal injection (B), and suprachoroidal injection through a microneedle (C). Intravitreal injection fills the vitreous body and exposes all intraocular surfaces in contact with the vitreous to the vectors or cells. Subretinal injection, delivers the therapeutic suspension immediately under the sensory retina, into the subretinal space, a virtual space between the photoreceptors and the retinal pigment epithelium (RPE). Suprachoroidal injection by a microneedle, delivers the therapeutic suspension into to the suprachoroidal space, a virtual space between choroid and sclera.