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Tumor response to chemotherapy and targeted therapy (crizotinib). A–C. The patient received etoposide and cisplatin for two cycles, but the primary tumor remained stable in size. After switching to crizotinib for 4 months, CT revealed shrinkage of primary tumor. D, E. Enhanced MRI of brain showed several nodules, and some of them disappeared after treatment with crizotinib for 4 months.
