TABLE 3.
MICs of β-lactams for E. coli TOP10 cells harboring recombinant plasmids pVHA-1 and pVHA-4 and environmental isolates of V. harveyi
| β-Lactam | MIC (μg/ml) of drug:
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
E. coli
|
V. harveyi
|
|||||||||||
| TOP10 | TOP10(pVHA1) | TOP10(pVHA4) | W3B | HB3 | M1 | E2 | GCB | P1B | AP5 | AP6 | M3.4L | |
| Ampicillin | 1 | 256 | 256 | 128 | 256 | 64 | 32 | >512 | 256 | >512 | 256 | 256 |
| Penicillin | 0.12 | >512 | 256 | 128 | 128 | 128 | 64 | >512 | 256 | 256 | 256 | 256 |
| Carbenicillin | 4 | >512 | >512 | >512 | >512 | 256 | 128 | >512 | >512 | >512 | >512 | >512 |
| Amoxicillin | 8 | >512 | >512 | 128 | 128 | 128 | 128 | 128 | 128 | 128 | 128 | 128 |
| Oxacillin | 128 | >512 | >512 | >512 | >512 | 128 | 128 | >512 | >512 | >512 | >512 | >512 |
| Imipenem | 0.125 | 0.125 | 0.125 | 0.25 | 0.125 | —a | — | — | — | — | — | — |
| Cephalothin | 8 | 8 | 8 | 16 | 16 | — | — | — | — | — | — | — |
| Cefotaxime | <0.03 | <0.03 | <0.03 | 1 | 1 | — | — | — | — | — | — | — |
a
—, not determined.