Figure 1. Regional distribution of brain PrP.
(A, C, and E) Diagrams of brain regions examined in humans, cynomolgus macaques, and mice, respectively, and (B, D, and F) PrP concentrations in n = 5 human, n = 6 macaque, and n = 8 mouse brains. Thin lines connect regions from the same individual. Bars indicate mean and 95% confidence interval of the mean. Red dashed lines indicate lower limit of quantification (LLQ). Brain diagrams were traced from Allen Brain Atlas images (51, 52).