Table 1. The most significant genetic correlation between each trait and a biochemical GWAS.
Biochemical trait | Psychiatric trait* | r g † | SE | P |
High light scatter reticulocyte percentage |
ADHD | 0.256 | 0.033 | 4.58 × 10–15 |
High light scatter reticulocyte count |
OCD | −0.212 | 0.046 | 3.37 × 10−6 |
CRP | AN | −0.286 | 0.038 | 9.76 × 10–14 |
Vitamin D | ASD | −0.177 | 0.047 | 2 × 10–4 |
Creatinine | BIP | −0.106 | 0.027 | 7.23 × 10–5 |
Leukocyte count | Cognition | −0.198 | 0.024 | 2.66 × 10–16 |
Leukocyte count | MDD | 0.155 | 0.025 | 9.77 × 10–10 |
Leukocyte count | PTSD | 0.225 | 0.043 | 1.37 × 10–7 |
Lymphocyte count | SZ | 0.075 | 0.017 | 1.52 × 10–5 |
Lymphocyte count | TS | −0.093 | 0.039 | 0.017 |
*Psychiatric GWAS: attention-deficit/hyperactivity disorder (ADHD), anorexia nervosa (AN), autism spectrum disorder (ASD), bipolar disorder (BIP), major depressive disorder (MDD), obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), SZ, and TS.
†rg is the estimate of genetic correlation from LDSR.