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. 2022 Apr 6;8(14):eabj8969. doi: 10.1126/sciadv.abj8969

Table 1. The most significant genetic correlation between each trait and a biochemical GWAS.

Biochemical trait Psychiatric trait* r g SE P
High light scatter reticulocyte
percentage
ADHD 0.256 0.033 4.58 × 10–15
High light scatter reticulocyte
count
OCD −0.212 0.046 3.37 × 10−6
CRP AN −0.286 0.038 9.76 × 10–14
Vitamin D ASD −0.177 0.047 2 × 10–4
Creatinine BIP −0.106 0.027 7.23 × 10–5
Leukocyte count Cognition −0.198 0.024 2.66 × 10–16
Leukocyte count MDD 0.155 0.025 9.77 × 10–10
Leukocyte count PTSD 0.225 0.043 1.37 × 10–7
Lymphocyte count SZ 0.075 0.017 1.52 × 10–5
Lymphocyte count TS −0.093 0.039 0.017

*Psychiatric GWAS: attention-deficit/hyperactivity disorder (ADHD), anorexia nervosa (AN), autism spectrum disorder (ASD), bipolar disorder (BIP), major depressive disorder (MDD), obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), SZ, and TS.

rg is the estimate of genetic correlation from LDSR.