Table 3.
Components of the Bexsero Vaccine
Component | Amount (per dose of 0.5 ml) | Relevant characteristics/function |
---|---|---|
FHbp (Factor H binding protein in fusion with the accessory protein GNA2091 | 50 µg | Negative regulatory protein of the alternative pathway of the complement |
NHBA (Neisserial Heparin Binding Antigen in fusion with the accessory protein GNA1030 | 50 µg | Complement dependent Bacterial lysis |
NadA (Neisserial Adhesin A | 50 µg | Binding to epithelial cells |
Vaccin OMV rMenB (strain NZ98/254, vaccin Men-ZB®) | 25 µg | Mainly PorA outer membrane protein |
Al(OH)3 | 1.5 mg | Adjuvant |