Figure 5.
PKHB1-KC induce tumor elimination in a prophylactic and therapeutic application. (A) Schema of PKHB1-KC or EPI-KC prophylactic application. (B) Graph indicates the mean of the tumor growth in mice treated with serum-free medium (Control; n = 10) or mice receiving a prophylactic vaccination with PKHB1-KC (Prophylactic-PKHB1-KC, n = 10) or EPI-KC (Prophylactic-EPI-KC, n = 10). (C) Kaplan–Meier survival graph of mice treated as in B over time. (D) Schema of PKHB1-KC or EPI-KC therapeutic application. (E) Graph indicates the mean of the tumor growth in mice treated with serum-free medium (Control; n = 9), PKHB1-KC (Therapeutic-PKHB1-KC, n = 9) or EPI-KC (Therapeutic-EPI-KC, n = 9), arrows indicate days of KC or serum-free medium inoculation. (F) Kaplan–Meier survival graph of mice treated as in E over time.