Figure 5.

IPC strategies in seed and production bioreactor steps for mAb1 and mAb2.Initial VCD was a PP for mAb1, while culture duration was a PP for mAb2. The only CPP identified was cell generation. The low limit for the final titer at harvest, as described in the process description, was normalized as 1 normalized weight/L. PA had no difference between two mAbs.

Alt Text: PP ranges for all PPs are listed on the left, PA ranges for all PAs are listed on the right, MAs and MPs are not listed, and only CPP identified is cell generation for mAb1 and mAb2 IPC strategies for n-2 seed bioreactor, n-1 seed bioreactor, and n production bioreactor steps.