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. 2022 Apr 1;13(1):609–633. doi: 10.1080/21505594.2022.2054760

Table 5.

MVD symptoms, according to the phase of infection

Phase of Infection Types of Symptoms Diagnostic Symptoms
Generalization Phase (day 1–5) General Symptoms High fever (39-40° C)
Severe headache
Myalgia
Chills
Malaise
Conjunctivitis
Dysphasia
Enanthem
Pharyngitis
Maculopapular rash
Lymphadenopathy
Leukopenia
Thrombocytopenia
Debilitating Symptoms Fatigue
Loss of appetite
Abdominal pain
Severe weight loss
Severe nausea
Vomiting
Watery diarrhea
Anorexia
Early Organ Phase (day 5–13) General Symptoms Conjunctival infection
Prostration
Dyspnea
Exanthema
Edema
Abnormal vascular permeability
Neurological Symptoms Confusion
Encephalitis
Irritability
Delirium
Aggression
Hemorrhagic Symptoms Mucosal bleeding
Melena
Petechiae
Bloody diarrhea
Visceral hemorrhagic effusions
Uncontrolled leakage from venipuncture sites
Hematemesis
Ecchymoses
Late Organ Phase/Convalescent Phase (day 13-20+) General Symptoms Severe metabolic disturbances
Convulsions
Severe dehydration
Multiorgan disfunction
Anuria
Orchitis
Myalgia
Exhaustion
Partial amnesia
Sweating
Peeled skin from rash areas
Secondary infection
Common complications during convalescent phase Arthralgia
Hepatitis
Asthenia
Ocular disease
Psychosis