Table 3.
Multivariable associations between GI symptomsc and nutritional intake in critically ill COVID-19 patients over time during first 14 days of ICU admission, presented separately for energy and protein intake (% calculated nutritional goal).
| Coefficienta | 95% CI | p-Valued | ||
|---|---|---|---|---|
| Energy intake | Diarrheab | 5.7% | −11.4; 22.8% | 0.512 |
| High GRVb | 7.6% | −8.5; 23.7% | 0.700 | |
| Moderate GI symptomsb | 42.7% | 16.5; 68.9% | 0.008 | |
| AGI score > IIb | 9.1% | −5.2; 23.3% | 0.627 | |
| Protein intake | Diarrheab | 7.2% | −7.6;-22.1% | 1.000 |
| High GRVb | −7.3% | −21.9; 7.2% | 1.000 | |
| Moderate GI symptomsb | 9.0% | −17.3; 35.2% | 0.499 | |
| AGI score > IIb | −6.1% | −19.0; 6.8% | 0.692 |
AGI, acute gastrointestinal injury; BMI, body mass index; CI, confidence interval; CRP, C-reactive protein; GI, gastro-intestinal, GRV, gastric residual volume; SOFA, sequential organ failure assessment.
Bold values in this table are considered significant (p < 0.05).
Exponent of the coefficients quantifies the increase or decrease in the average of the main outcome.
Adjusted for age, gender, BMI (kg/m2), comorbidities(y/n), SOFA score, and CRP (mg/l).
Since vomiting and abdominal distention occurred in <5% of the patients, they were not taken into account.
P-values were corrected for multiple testing.