Table 3.

Comparison of specific features of diagnostic algorithms

Features	InterVA5	InSilicoVA	SmartVA/Tariff
Computing platform compatibility	Windows MacOs Linux	Windows MacOs Linux	Windows only
Number of indicators used by algorithm	304	304	211
Exact implementation/replication in openVAa	Yes	Yes	No
Implementation without training dataset	Yes	Yes	No
Can produce instantaneous results for a single death	Yes	No	Yes
Only significant symptoms used at individual level	No	No	Yes
Accounts for absence of symptoms	No	Yes	No
Accounts for missing symptoms	No	Yes	No
Provides distribution of probabilities for each cause for a single death	Yes	Yes	No
Provides measure of uncertainty for individual cause assignments	No	Yes	No
Direct estimation of cause-specific mortality fractions	No	Yes	No
Provides a distribution of probabilities for each CSMF	No	Yes	No
Provides uncertainty measure for cause-specific mortality fractions	No	Yes	No

^aSource: Samuel J. Clark, openVA development team. www.openva.net.