Table 2.
Surgical management for HCC patients with a high risk of MVI.
| Author | Years | Study types | No. of studies | No. of patients | Therapy | RFS (%) | OS (%) |
|---|---|---|---|---|---|---|---|
| Imai et al. | 2018 | Retrospective study | 1 | 159 | RFA (without MVI vs. with MVI) | 5-year DFS 11.6% vs. 6.8%，P = 0.20 | 5-year 80.0% vs. 55.8%，P = 0.0037 |
| Li et al. | 2021 | Retrospective study | 1 | 516 | RFA vs. SR | 2-year 30.6% vs. 90.0% | / |
| Sun et al. | 2021 | Meta-analysis | 12 | 1550 | AR vs. NAR | 5-year 37.72% vs. 27.51%, P < 0.001 | 5-year 61.7% vs. 59.17%, P < 0.001 |
| Yang et al. | 2019 | Retrospective study | 1 | 904 | Narrow margin group (<2 mm) vs. a wide-margin group (>2 mm) | 5-year 56.7% vs. 25.4%, P < 0.001 | 5-year 76.3% vs. 56.8%, P < 0.001 |
| Han et al. | 2020 | Retrospective study | 1 | 929 | Narrow margin group (<1 cm) vs. a wide-margin group (>1 cmm) | 5-year 71.1% vs. 85.9%, P < 0.001 | 5-year 44.9% vs. 25.0%, P < 0.001 |
RFA: radiofrequency ablation; MVI: microvascular invasion; SR: surgical resection; AR: anatomic resection; NAR: nonanatomical resection.