Table 3.

Management of HCC patients with MVI after R0 liver resection.

Author	Years	Study types	No. of studies	No. of patients	Therapy	RFS (%)	OS (%)
Sun et al.	2015	Retrospective	1	322	Surgical resection plus TACE vs. surgical resection only	5 year DFS 35.0% vs.30.3%，P = 0.012	5-year 54.0% vs. 43.2%，P = 0.006
Ye et al.	2017	PSM and retrospective	1	260	Surgical resection plus TACE vs. surgical resection only	4 year DFS 30.9% vs 28.4%，P = 0.002	4-year 67.5% vs 53.9%；P = 0.019
Chen et al.	2020	Meta-analysis	12	2190	Surgical resection plus TACE vs. surgical resection only	5-year OR: 0.58; 95% CI: 0.46~0.73.	5-year OR: 0.59; 95% CI: 0.48~0.73
Gu et al.	2020	Meta-analysis	4	955	Surgical resection plus sorafenib vs. surgical resection only	HR 1.369, 95% CI 1.193~1.570	/