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. 2022 Mar 6;14(3):e22899. doi: 10.7759/cureus.22899

Table 3. Pediatric patients with a known diagnosis of epilepsy and presentation with COVID-19 infection with outcomes.

GTC = generalized tonic-clonic; LoC = loss of consciousness; Bi-PLEDs = bilateral independent periodic lateralized epileptiform discharges.

Authors Age, sex Prior diagnosis of epilepsy  Neurological symptoms Non-neurological symptoms EEG Prognosis
Atakla et al. (2020) [16] 14 years, male Known generalized epilepsy since the age of nine years. Well managed on maintenance Depakote Worsening GTC seizures, confusion, and LoC Fever and flu-like symptoms 4-5 Hz theta activity, ample, symmetrical, bilateral, and associated with epileptogenic discharges in the right hemisphere, suggesting multifocal epilepsy Recovered
Zombori et al. (2021) [17] 17 years, female Cornelia de Lange syndrome and well-controlled generalized epilepsy Pediatric multi-inflammatory syndrome temporally related to COVID-19 (PIMS-TS) Fever Bi-PLEDs and subclinical seizures Worsening neurodisability