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. 2022 Mar 30;604(7904):167–174. doi: 10.1038/s41586-022-04598-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 4 — a, Immunofluorescence experiments showing colocalization of rixosome subunits MDN1 and WDR18 with the nucleolar marker NPM1 in wild-type (WT) and EZH1/2 double knockout cells, and with NPM1 and EZH2 in RING1A/B double knockout cells. Scale bar, 5 μm. b, c, Quantification of change in MDN1 (b) or NPM1 (c) foci per nucleus in the indicated cells. p values are from two-sided student’s t-tests. Data are presented as mean values +/− SEM.

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