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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Adv Healthc Mater. 2021 Dec 17;11(7):e2101534. doi: 10.1002/adhm.202101534

Figure 5. In vivo impact of Poly-A particles on neutrophil accumulation and surface protein expression 1-hour post-injection.

Figure 5.

(A) Schematic showing experimental timing and set up. (B) Neutrophil concentration in blood 2-hours post LPS instillation and 1-hour post-injection. (C) Neutrophil accumulation in the liver post LPS instillations and particle injections. (D) Particle Positive neutrophil accumulation in the liver. Fold decrease in PSGL-1 expression compared to untreated neutrophils in the (E) blood and (F) neutrophils isolated from the liver. P+ Nøs = Particle positive neutrophils. Statistical analysis was performed using GraphPad Prism Software using One-Way ANOVA with Fisher’s LSD test with a 95% confidence interval. Asterisks indicate p values of: * = p < 0.05, ** = p < 0.01. N≥3 for this experiment.