Table 2.

Cox proportional hazard models for time to neurocognitive decline comparing Latino and White people with HIV (Model A) and Latinos and Black people with HIV (Model B)

Model A	Predictor	Reference	Risk	HR (95% CI)	P Value
Model 1A
	Ethnicity/race	White	Latino	2.25 [1.35, 3.73]	0.002
Model 2A
	Ethnicity/race	White	Latino	1.83 [1.06, 3.16]	0.03
	Hematocritc	1 unita	Lower	1.08 [1.02, 1.14]	0.006
	Comorbidity	Contributing	Confounding	3.16 [1.44, 6.93]	0.004
	Comorbidity	Incidental	Confounding	3.38 [1.69, 6.73]	<0.001
	Total Cholesterolc	1 unita	Lower	1.01 [1.00, 1.02]	0.04
	Triglyceridesc	1 unitb	Higher	1.00 [1.00, 1.03]	0.07
Model B	Predictor	Reference	Risk	HR (95% CI)	P Value
Model 1B
	Ethnicity/race	Black	Latino	1.86 [1.14, 3.04]	0.013
Model 2B
	Ethnicity/race	Black	Latino	2.39 [1.34, 4.19]	0.002
	Nadir CD4	1 sqrtb	Higher	1.04 [1.00, 1.07]	0.06
	Hematocritc	1 unita	Lower	1.08 [1.02, 1.14]	0.009
	Diabetesc	No	Yes	1.69 [0.85, 3.34]	0.13
	Urine toxicologyc	Negative	Positive	1.61 [0.91, 2.87]	0.10

Abbreviations: HR, hazard ratio; CI, confidence interval; sqrt, square root transformation; CD4, cluster of differentiation 4; Comorbidity, Neurocognitive Comorbidity Status; LT Meth SUD, lifetime methamphetamine substance use disorder

Notes:

^aHigher

^bLower

^cVariable modelled in a time-dependent manner