Table 1.
Demographic and clinical characteristics, by myocardial infarction status, of people with HIV from five CNICS sites across the US (N=12,448).
| N (%) or Mean (SD) | No MI | T1MI | T2MI | Overall |
|---|---|---|---|---|
| N | 12,181 (97.9%) | 158 (1.3%) | 109 (0.9%) | 12,448 |
| Age | 43 (11) | 51 (8) | 49 (11) | 43 (11) |
| Female | 1,905 (16%) | 13 (8%) | 23 (21%) | 1,941 (16%) |
| Race/Ethnicity | ||||
| Non-Hispanic White | 5,677 (47%) | 87 (55%) | 46 (42%) | 5,810 (47%) |
| Non-Hispanic Black | 3,842 (32%) | 41 (26%) | 51 (47%) | 3,934 (32%) |
| Hispanic | 1,996 (16%) | 24 (15%) | 10 (9%) | 2,030 (16%) |
| Other/unknown | 666 (5%) | 6 (4%) | 2 (2%) | 674 (5%) |
| CD4 count (cells/mm3) | 541 (306) | 495 (316) | 398 (296) | 539 (307) |
| Currently taking ART | 11,518 (95%) | 150 (95%) | 103 (95%) | 11,771 (95%) |
| Undetectable VL (≤400 copies/ml) | 9,837 (81%) | 121 (77%) | 75 (69%) | 10,033 (81%) |
| Diabetes a | 962 (8%) | 35 (22%) | 23 (21%) | 1,020 (8%) |
| Hypertension b | 2,635 (22%) | 81 (51%) | 44 (40%) | 2,760 (22%) |
| Dyslipidemia c | 1,918 (16%) | 68 (43%) | 32 (29%) | 2,018 (16%) |
| CKD (eGFR, <30 mL/min/1.73 m2) | 108 (0.9%) | 9 (6%) | 12 (11%) | 129 (1%) |
| Current cigarette smoker | 4,456 (37%) | 77 (49%) | 51 (47%) | 4,584 (37%) |
| Insomnia – difficulty falling or staying asleep | ||||
| I do not have symptom | 5,309 (44) | 63 (40) | 36 (33) | 5,408 (43) |
| I have symptoms but it does not bother me | 1,084 (9) | 18 (11) | 7 (6) | 1,109 (9) |
| I have symptoms and it bothers me a little | 2,286 (19) | 27 (17) | 26 (24) | 2,339 (19) |
| I have symptoms and it bothers me | 1,643 (13) | 22 (14) | 23 (21) | 1,688 (14) |
| I have symptoms and it bothers me a lot | 1,859 (15) | 28 (18) | 17 (16) | 1,904 (15) |
Abbreviations: ART, antiretroviral therapy; CNICS; Centers for AIDS Research Network of Integrated Clinical Systems; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; MI, myocardial infarction; T1MI, type 1 myocardial infarction; T2MI, type 2 myocardial infarction; VL, viral load.
Diabetes is defined as any one of the following: hemoglobin A1c ≥ 6.5%, a clinical diagnosis of diabetes and prescription of a diabetes-related medication, or prescription of a diabetes-specific medication.
Hypertension is defined as a clinical diagnosis of hypertension and prescription of an antihypertensive medication.
Dyslipidemia is defined as a lipid abnormality requiring statin treatment.