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. 2021 Jul 6;480(2):481–486. doi: 10.1007/s00428-021-03140-3

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Representative histological images of Case 1 show epithelioid cells disposed into communicating irregular nests within fibrous stroma (A) with focal entrapment of the glomeruli (B). C At high power, the epithelioid morphology is seen; note the variably granular eosinophilic to clear cytoplasm. D AE1/AE3 reveals mainly paranuclear dot-like pattern (note the strong expression in entrapped tubules; main image). D, inset, PAX8 highlights entrapped tubules, but the tumor cells are negative. E Strong cytoplasmic ALK expression is seen. F MUC4 is variably positive