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Angiopoietin-like protein 3 (ANGPTL3) and apolipoprotein C-III (apoC-III) inhibition may be equally effective in correcting hypertriglyceridaemia in chylomicronaemia syndromes, metabolic-associated fatty liver disease, insulin resistance/diabetes and mixed hyperlipidaemia, but ANGPTL3 inhibition may more effectively lower low-density lipoprotein (LDL) cholesterol and have extended applications in mixed atherogenic dyslipidaemia and more severe forms of familial hypercholesterolaemia
