Table 2.
Migraine features and clinical characteristics of patients with migraine existing before start with combined hormonal contraception (CHC) (group 1) and women whose migraine started after having initiated CHC use (group 2)
| Migraine feature n | All n = 48 | Group 1 n = 22 | Group 2 n = 26 | p value |
|---|---|---|---|---|
| Menstrually related attacks are more painful than others* % (n) | 57.5 (26) | 72.7 (16) | 43.4 (10) 23n | 0.015 |
| Menstrually related attacks respond good to pain medication* % (n) | 47.8 (22) | 31.8 (7) | 65.2 (15) | 0.05 |
| Pain location: unilateral mostly or always % (n) | 95.1 (39) | 95 (19) | 95,2 (20) | 0.99 |
| Family history positive % (n) | 72.9 (35) | 86.4 (19) | 61.5 (16) | 0.05 |
| Medication overuse headache in the past % (n) | 10.4 (5) | 10.0 (2) | 11.5 (3) | 0.62 |
| Status migrainosus ever % (n) | 41.7 (20) | 47.6 (10) | 38.5 (10) | 0.42 |
| Triptan use as acute medication % (n) | 40.9 (18) | 27 (5) | 54.2 (13) | 0.04 |
| Ever use of prophylactic agents % (n) | 8.9 (6) | 3.2 (1) | 19.2 (5) | 0.76 |
| Non-hormonal trigger yes % (n) | 81.1 (39) | 81.8 (18) | 80.8 (21) | 0.61 |
| Associated symptoms % (n) | 87.5% (42) | 86.4 (19) | 88.5 (23) | 0.58 |
| Nausea % (n) | 62.5 (30) | 54.5 (12) | 69.0 (18) | 0.22 |
| Vomiting % (n) | 29.2 (14) | 18.2 (4) | 38.5 (10) | 0.20 |
| Photophobia % (n) | 64.6 (31) | 63.6 (14) | 65.4 (17) | 0.57 |
| Phonophobia % (n) | 45.8 (22) | 36.4 (8) | 53.8 (14) | 0.26 |
| Endometriosis % (n) | 0 (0) | 0 (0) | 0 (0) | 0.99 |
| Depression % (n) | 4.3% (2) | 0 (0) | 7.7 (2) | 0.31 |
| Other types of chronic pain % (n) | 4.3% (2) | 0 (0) | 7.6 (2) | 0.41 |
| History of traumatic brain injury, meningitis, concussion % (n) | 0 (0) | 0 (0) | 0 (0) | 1.0 |
| History of stroke % (n) | 0 (0) | 0 (0) | 0 (0) | 1.0 |
*Three participants from group 2 with PMM were excluded from this analysis