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. 2022 Jan 24;76(1):132–141. doi: 10.1007/s12020-022-02983-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Patient journey throughout care process of apoplexy type A, B, and C patients. This figure illustrates the patient journey of apoplexy type A, B, and C patients throughout their care process until they reach treatment start. T1, time period in days between onset of apoplexy symptoms and first presentation in hospital (one way ANOVA between groups yielded p < 0.001); T2, time period in days between first presentation in hospital and moment of diagnosing pituitary apoplexy (one way ANOVA between groups yielded p < 0.001); T3, time period in days between first presentation in hospital and treatment start (one way ANOVA between groups yielded p < 0.001); Proportion of patients that were seen in a regional versus academic hospital at first presentation did not differ significantly between groups (chi-square yielded p = 0.917). Proportion of patients that were admitted to an inpatient ward in the hospital after first presentation did differ significantly between groups (chi-square yielded p < 0.001). The in hospital locations where patients were seen at their first hospital presentation significantly differed between the groups, with type A patients presenting primarily at the emergency department and almost all type C patients at the outpatient clinic (chi-square yielded p < 0.001). Proportion of patients that were treated either surgically or conservatively did not differ significantly between groups (chi-square yielded p = 0.248). Proportion of surgically treated patients that either had emergency (<3 days) or more elective (>3 days) surgery did differ significantly between groups (chi-square yielded p < 0.001)