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. 2022 Jan 24;76(1):132–141. doi: 10.1007/s12020-022-02983-3

Table 3.

Symptoms at first presentation in hospital of pituitary apoplexy type A, B, and C patients

Symptom at first hospital presentation Type A N = 51 Type B N = 22 Type C N = 25 Total N = 98 p-value
Any headache (N) 98.0 (49/50) 90.9 (20/22) 76.0 (19/25) 90.7 (88/97) 0.008
 Acute onset < 3 days (N) 98.0 (48/49) 55.0 (11/20) 10.5 (2/19) 69.3 (61/88) <0.001
 No acute onset (N) 2.0 (1/49) 45.0 (9/20) 89.5 (17/19) 30.7 (27/88) <0.001
Normal consciousness (N) 82.0 (41/50) 100 (22/22) 100 (25/25) 90.7 (88/97) 0.053
 Slightly lowered (N) 12.0 (6/50) 0.0 (0/22) 0.0 (0/25) 6.2 (6/97) 0.053
 Lowered (N) 6.0 (3/50) 0.0 (0/22) 0.0 (0/25) 3.1 (3/97) 0.053
Visual acuity ODS (SD) 0.72 (0,39) 0.90 (0.32) 1.02 (0.12) 0.84 (0.35) 0.002
Visual acuity of the worst eye (SD) 0.62 (0,44) 0.82 (0.36) 0.96 (0.16) 0.76 (0.39) 0.002
VFD (N) 66.7 (34/51) 63.6 (14/22) 32.0 (8/25) 57.1 (56/98) 0.013
CN. III, IV or VI palsy (N) 66.7 (34/51) 27.3 (6/22) 8.0 (2/25) 42.9 (42/98) <0.001
Nausea (N) 58.8 (30/51) 40.9 (9/22) 8.0 (2/25) 41.8 (41/98) <0.001
Vomiting (N) 56.9 (29/51) 27.3 (6/22) 8.0 (2/25) 37.8 (37/98) <0.001
Fever without focus (N) 24.0 (12/50) 4.5 (1/22) 8.0 (2/25) 15.5 (15/97) 0.053
Loss of at least one axis (N) 80.4 (41/51) 68.2 (15/22) 60.0 (15/25) 72.4 (71/98) 0.153
 Hypocortisolism (N) 62.7 (32/51) 31.8 (7/22) 36.0 (9/25) 49.0 (48/98) 0.017
 Hypothyroidism (N) 64.7 (33/51) 59.1 (13/22) 40.0 (10/25) 57.1 (56/98) 0.121
 Hypogonadism (N) 56.9 (29/51) 45.5 (10/22) 44.0 (11/25) 51.0 (50/98) 0.481
 Hyposomatotropism (N) 39.2 (20/51) 18.2 (4/22) 15.0 (4/25) 28.6 (28/98) 0.052
 Hyperprolactinemia (N) 11.8 (6/51) 36.4 (8/22) 44.0 (11/25) 25.5 (25/98) 0.004
 Diabetes insipidus (N) 5.9 (3/51) 4.5 (1/22) 4.0 (1/25) 5.1 (5/98) 0.932

Data are presented as mean ± SD or % (N) unless stated otherwise. SD standard deviation, N number, ODS both left and right eye, VFD Visual field defects, CN Cranial nerve