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. 2022 Apr 6;5:326. doi: 10.1038/s42003-022-03251-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a, b Expression level of GSTM2 was detected in shGSTM2-HepG2 cells and corresponding control cells. c More LDs were observed in shGSTM2-HepG2 cells. d Statistics of LD number in shGSTM2-HepG2 cells and shNC-HepG2 cells. e More larger LDs were found in shGSTM2-HepG2 cells treated with 1 mM oleic acid medium for 12 h compared to control cells. f Statistics of LD diameter in shGSTM2-HepG2 cells and shNC-HepG2 cells treated with 1 mM oleic acid medium for 12 h compared to control cells. g Cellular ROS level was detected in shGSTM2-HepG2 and shNC-HepG2 cells in the presence or absence of oleic acid medium; *p < 0.05, **p < 0.01. h More LDs were observed in cells treated with ROSup compared to control cells. i Statistics of LD number in cells treated with ROSup and control cells. Bar, 10 μm.