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. 2022 Apr 6;12:5724. doi: 10.1038/s41598-022-09730-8

Table 2.

Factors associated with infections by the two genomic subtypes of EPEC across each of the eight study sites (Bangladesh, India, Nepal, Pakistan, South Africa, Tanzania, Brazil, and Peru) from November 2009 to February 2012.

Factors tEPEC aEPEC
IRR (95% CI) P value IRR (95%CI) P value
Sex
Male 1.06 (0.99, 1.13) 0.054 1.00 (0.96, 1.03) 1.00
Exclusive BF (months) 1.00 (0.99, 1.00) 0.901 0.99 (0.99, 1.00) < 0.001
Cattle
Yes 0.90 (0.80, 1.02) 0.096 0.94 (0.88, 1.01) 0.086
Chickens
Yes 1.02 (0.93, 1.13) 0.647 1.03 (0.98, 1.08) 0.247
WAZ 0.99 (0.96, 1.03) 0.706 1.01 (0.99, 1.03) 0.313
Improved floor
Yes 0.93 (0.84, 1.03) 0.175 0.99 (0.94, 1.05) 0.706
Improved drinking water source
Yes 0.98 (0.86, 1.11) 0.699 1.00 (0.93, 1.07) 0.943
Use water treatment method
Yes 0.96 (0.87, 1.06) 0.418 1.00 (0.95, 1.05) 0.972
Improved sanitation
Yes 0.90 (0.81, 0.99) 0.026 0.98 (0.93, 1.04) 0.459
Maternal Age 0.99 (0.99, 1.00) 0.059 1.00 (0.99, 1.00) 0.295
Mother has < 3 living children
Yes 0.93 (0.86, 1.01) 0.103 0.96 (0.92, 1.01) 0.119
< 2 people live in per room
Yes 0.99 (0.91, 1.07) 0.75 0.98 (0.94, 1.02) 0.356
Monthly income < 150 USD
Yes 1.05 (0.96, 1.14) 0.287 1.00 (0.95, 1.05) 0.998
Maternal education (years) 0.99 (0.98, 1.00) 0.054 1.00 (0.99, 1.00) 0.162
Country
Brazil 0.17 (0.14, 0.22) < 0.001 0.71 (0.65, 0.79) < 0.001
India 0.76 (0.67, 0.87) < 0.001 0.99 (0.92, 1.07) 0.839
Nepal 0.34 (0.29, 0.40) < 0.001 0.87 (0.81, 0.94) 0.001
Peru 0.62 (0.53, 0.73) < 0.001 0.88 (0.81, 0.97) 0.010
Pakistan 0.44 (0.37, 0.53) < 0.001 0.48 (0.43, 0.53) < 0.001
South Africa 0.23 (0.19, 0.28) < 0.001 0.60 (0.54, 0.66) < 0.001
Tanzania 0.82 (0.66, 1.02) 0.070 1.13 (1.00, 1.27) 0.057

Model: Poisson regression; IRR: Incidence rate ratio; aWAZ: Weight-for-age z score.

Dependent variable: Number of infections during follow up (1–24 m).

Offset: Log of the total number of follow up; alpha (α): dispersion parameter.

Adjusted for the site and all variables included in the multivariable model.