Table 2.
Factors associated with infections by the two genomic subtypes of EPEC across each of the eight study sites (Bangladesh, India, Nepal, Pakistan, South Africa, Tanzania, Brazil, and Peru) from November 2009 to February 2012.
| Factors | tEPEC | aEPEC | ||
|---|---|---|---|---|
| IRR (95% CI) | P value | IRR (95%CI) | P value | |
| Sex | ||||
| Male | 1.06 (0.99, 1.13) | 0.054 | 1.00 (0.96, 1.03) | 1.00 |
| Exclusive BF (months) | 1.00 (0.99, 1.00) | 0.901 | 0.99 (0.99, 1.00) | < 0.001 |
| Cattle | ||||
| Yes | 0.90 (0.80, 1.02) | 0.096 | 0.94 (0.88, 1.01) | 0.086 |
| Chickens | ||||
| Yes | 1.02 (0.93, 1.13) | 0.647 | 1.03 (0.98, 1.08) | 0.247 |
| WAZ | 0.99 (0.96, 1.03) | 0.706 | 1.01 (0.99, 1.03) | 0.313 |
| Improved floor | ||||
| Yes | 0.93 (0.84, 1.03) | 0.175 | 0.99 (0.94, 1.05) | 0.706 |
| Improved drinking water source | ||||
| Yes | 0.98 (0.86, 1.11) | 0.699 | 1.00 (0.93, 1.07) | 0.943 |
| Use water treatment method | ||||
| Yes | 0.96 (0.87, 1.06) | 0.418 | 1.00 (0.95, 1.05) | 0.972 |
| Improved sanitation | ||||
| Yes | 0.90 (0.81, 0.99) | 0.026 | 0.98 (0.93, 1.04) | 0.459 |
| Maternal Age | 0.99 (0.99, 1.00) | 0.059 | 1.00 (0.99, 1.00) | 0.295 |
| Mother has < 3 living children | ||||
| Yes | 0.93 (0.86, 1.01) | 0.103 | 0.96 (0.92, 1.01) | 0.119 |
| < 2 people live in per room | ||||
| Yes | 0.99 (0.91, 1.07) | 0.75 | 0.98 (0.94, 1.02) | 0.356 |
| Monthly income < 150 USD | ||||
| Yes | 1.05 (0.96, 1.14) | 0.287 | 1.00 (0.95, 1.05) | 0.998 |
| Maternal education (years) | 0.99 (0.98, 1.00) | 0.054 | 1.00 (0.99, 1.00) | 0.162 |
| Country | ||||
| Brazil | 0.17 (0.14, 0.22) | < 0.001 | 0.71 (0.65, 0.79) | < 0.001 |
| India | 0.76 (0.67, 0.87) | < 0.001 | 0.99 (0.92, 1.07) | 0.839 |
| Nepal | 0.34 (0.29, 0.40) | < 0.001 | 0.87 (0.81, 0.94) | 0.001 |
| Peru | 0.62 (0.53, 0.73) | < 0.001 | 0.88 (0.81, 0.97) | 0.010 |
| Pakistan | 0.44 (0.37, 0.53) | < 0.001 | 0.48 (0.43, 0.53) | < 0.001 |
| South Africa | 0.23 (0.19, 0.28) | < 0.001 | 0.60 (0.54, 0.66) | < 0.001 |
| Tanzania | 0.82 (0.66, 1.02) | 0.070 | 1.13 (1.00, 1.27) | 0.057 |
Model: Poisson regression; IRR: Incidence rate ratio; aWAZ: Weight-for-age z score.
Dependent variable: Number of infections during follow up (1–24 m).
Offset: Log of the total number of follow up; alpha (α): dispersion parameter.
Adjusted for the site and all variables included in the multivariable model.