Table 3.
Clinical, medication, and patient-reported outcomes (at baseline survey, B) predictive of subsequent hospitalization (reported at F1) in patients with IBD, by Crohn’s disease and ulcerative colitis
| Crohn’s disease | Ulcerative Colitis | |
|---|---|---|
| Odds ratio (95% Confidence Interval) | Odds ratio (95% Confidence Interval) | |
| Clinical characteristics | ||
| Age at diagnosis (per 1 y) | - | 0.98 (0.97 – 0.99) |
| Women (%) | - | - |
| BMI | 0.97 (0.96 – 0.99) | 0.98 (0.95 – 1.00) |
| Education (% >college) | - | 0.55 (0.33 – 0.92) |
| Disease duration (per 1 y) | 1.01 (1.00 – 1.01) | - |
| History of hospitalization (%) | 1.17 (0.96 – 1.43) | 1.34 (0.98 – 1.83) |
| History of bowel surgery ever (%) | - | - |
| Recent bowel surgery since the last survey | 1.36 (0.91 – 2.03) | - |
| Patients in clinical remission | 0.52 (0.43 – 0.62) | 0.48 (0.33 – 0.68) |
| Current Medications | ||
| Narcotics | - | - |
| Biologics | 1.42 (1.21 – 1.66) | - |
| Steroids | 1.56 (1.29 – 1.88) | 2.30 (1.64 – 3.23) |
| Immunomodulator | 0.85 (0.72 – 1.01) | - |
| 5-ASA | 0.88 (0.74 – 1.05) | 0.61 (0.44 – 0.84) |
| PROMIS Domains (per 5 points increase in PROMIS scores)- | ||
| Anxiety domain | 0.96 (0.89 – 1.02) | |
| Depression domain | 1.07 (0.99 – 1.15) | 0.86 (0.77 – 0.96) |
| Fatigue domain | - | - |
| Sleep disturbance domain | - | - |
| Increased participation in social events domain | - | 0.88 (0.79 – 0.97) |
| Pain interference domain | 1.11 (1.06 – 1.17) | 1.12 (1.01 – 1.23) |
Backwards logistic regression model was utilized. Variables that did not make it into the final regression model did not have an odds ratio reported.