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RCI001 suppressed the Rac1-GTP complex formation in lipopolysaccharide-stimulated RAW 264.7 (A, B); and dose-dependently inhibited Rac1 activity (C) in CN04-stimulated Swiss 3T3 cells without affecting RhoA (D) and Cdc42 (E). Data are means ± standard error of the mean (SEM). ** p<0.01, and ***p<0.001. LPS, RAW 264.7 cells stimulated with lipopolysaccharide; RCI001, application of RCI001 on lipopolysaccharide-stimulated RAW 264.7 cells.
