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. 2022 Mar 24;13:850287. doi: 10.3389/fimmu.2022.850287

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Copyright © 2022 Kim, Jang, Ku, Shin, Rahman, Chung, Kim and Kim

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Therapeutic effects of topical RCI001 (8-oxo-dG) on histological changes of the cornea in alkali burn induced ocular surface disease model. (A–C) Representative images of hematoxylin and eosin (H&E) staining of the central cornea. (D) Comparison of stromal thickness of the central cornea. Yellow bar- epithelium, blue bar- stroma and green bar- endothelium whereas black bar indicates size 50 μm. Data are reported as means SEMs (n = 10). ***p < 0.001, Bonferroni post hoc test following one-way ANOVA.