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. 2022 Mar 24;13:829228. doi: 10.3389/fimmu.2022.829228

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Copyright © 2022 Vietzen, Döhler, Tran, Süsal, Halloran, Eskandary, Herz, Mayer, Kozakowski, Wahrmann, Ely, Haindl, Puchhammer-Stöckl and Böhmig

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Recipient KLRC2 variant distribution among (A) donor-specific antibody (DSA)+ study patients versus propensity score-matched DSA– control subjects (patients selected from the BORTEJECT trial), and (B) donors versus recipients of the Collaborative Transplant Study (CTS) study cohort. Genotype frequencies in the CTS recipient population deviated from Hardy Weinberg equilibrium (P = 0.008), but not the donor-specific antibody (DSA)+ (P = 0.31), DSA– (P=0.10) and CTS donor cohorts (P = 0.29), respectively.