Table 5.
Multivariable Cox regression analysis for influence of number of KLRC2-wild type alleles on 10-year graft and patient survival in the CTS cohort.
| Population | Patients | Death-censored graft survival | Overall graft survival | Patient survival | |||
|---|---|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | ||
| All patients | 1,860 | 0.94 (0.81–1.10) | 0.44 | 0.95 (0.84–1.07) | 0.38 | 0.91 (0.78–1.06) | 0.24 |
| PRA>0% | 412 | 0.97 (0.68–1.40) | 0.89 | 0.92 (0.69–1.23) | 0.57 | 0.88 (0.61–1.27) | 0.50 |
| 4–6 mismatches a | 680 | 0.85 (0.66–1.09) | 0.20 | 0.86 (0.71–1.04) | 0.11 | 0.83 (0.65–1.06) | 0.14 |
| 1-year-rej | 227 | 0.95 (0.59–1.53) | 0.83 | 0.91 (0.62–1.35) | 0.65 | 0.78 (0.46–1.31) | 0.35 |
CTS, Collaborative Transplant Study; PRA, panel-reactive antibodies; rej, rejection treatment.
a
HLA-A+B+DR mismatch.
Hazard ratios (HR) and 95% confidence interval (CI) per wild type allele are shown.