TABLE 1.
Sample characteristics.
| Placebo (N = 40) |
Reference (N = 20) |
P | |
| Age (years) | 25.9 ± 5.2 | 24.6 ± 3.0 | 0.29 |
| Sex (N female/N male) | 20/20 | 9/11 | 0.72 |
| Body mass index (kg/m2) | 23.0 ± 2.8 | 22.4 ± 2.2 | 0.34 |
| HADS anxiety score | 3.6 ± 2.8 | 2.6 ± 2.1 | 0.16 |
| HADS depression score | 2.1 ± 2.1 | 1.0 ± 1.4 | 0.04 |
| STAI trait score | 35.4 ± 7.3 | 33.1 ± 7.5 | 0.26 |
| GI symptom score | 4.1 ± 2.8 | 3.6 ± 2.9 | 0.57 |
| Rectal sensory threshold, mmHg | 14.9 ± 3.8 | 14.2 ± 3.0 | 0.47 |
| Rectal pain threshold, mmHg | 35.0 ± 10.7 | 34.6 ± 7.4 | 0.88 |
Data are shown as mean ± standard deviation, unless otherwise indicated. No significant group differences were observed between the Placebo and Reference groups (P values indicate results of independent sample t-tests or Chi2 tests for sex). GI, gastrointestinal; HADS, Hospital Anxiety and Depression Scale; STAI, State-Trait Anxiety Inventory.