Table 2.
The receptors in the main comberon of human choroid endothelial cells.
| Receptors | Frequency | Pubmed angiogenesis | Strongest Experimental evidence |
|---|---|---|---|
| BMPR2 | 0.9 | 92 | |
| PTPRG | 0.9 | 3 | |
| PTPRB | 0.89 | 9 | |
| NOTCH1 | 0.87 | 388 | |
| PTPRM | 0.86 | 0 | |
| ENG | 0.85 | 891 | |
| IL6ST | 0.82 | 13 | LIFR co-receptor |
| LIFR | 0.82 | 8 | Our LIF experimental paper (Li et al., 15 |
| NRP1 | 0.8 | 399 | KDR co-receptor |
| PLXND1 | 0.78 | 31 | |
| ITGA5 | 0.77 | 18 | |
| OSMR | 0.75 | 9 | |
| PECAM1 | 0.75 | 404 | |
| CD46 | 0.74 | 22 | |
| CDH5 | 0.74 | 51 | |
| KDR | 0.74 | 1952 | main VEGFA receptor |
| ROBO4 | 0.74 | 74 | |
| TEK | 0.74 | 210 | |
| TGFBR2 | 0.74 | 194 | |
| TIE1 | 0.74 | 205 | |
| ADIPOR2 | 0.73 | 11 | |
| S1PR1 | 0.71 | 68 | |
| CFH | 0.7 | 69 | Main genetic risk factor for AMD |
| IL4R | 0.7 | 13 | |
| ITGAV | 0.7 | 26 |
All the receptors with substantial evidence for a role in angiogenesis are shown in Bold.