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. 2022 Mar 24;16:838968. doi: 10.3389/fnhum.2022.838968

Table 3.

Results of moderator analyses for pre-post comparisons between combined training vs. control, cognitive or physical single for cognitive and physical outcomes.

Outcomes Level 2 variance (%) Level 3 variance (%) Omnibus testa QE Comparison groups # Studies # ES Mean difference in ES [95% CI]
Cognitive functions
Executive functions 0.00 (7.811e-08) 0.024 (22.971)*** F(2, 161) = 0.42,
p = 0.657
189.618 Combined vs. control 21 80 0.2 [0.103, 0.297]***
Combined vs. cognitive 13 44 0.144 [0.021, 0.267]*
Combined vs. physical 14 40 0.199 [0.081, 0.316]***
Memory 0.000 (4.286e-08) 0.039 (36.098)*** F(2, 138) = 5.051,
p = 0.008
251.221*** Combined vs. control 19 50 0.204 [0.088, 0.321]**
Combined vs. cognitive 15 43 0.007 [-0.119, 0.134]
Combined vs. physical 17 48 0.117 [-0.017, 0.256]*
Attention 0.019 (17.262) 0.02 (18.141) F(2, 47) = 5.176,
p = 0.009
71.632* Combined vs. control 10 28 0.197 [0.038, 0.358]*
Combined vs. cognitive 8 11 −0.166 [-0.383, 0.051]
Combined vs. physical 7 11 0.19 [-0.015, 0.396]
Language 0.00 (7.64e-09) 0.036 (45.287)*** F(2, 31) = 3.387,
p = 0.047
30.875* Combined vs. control 6 11 0.305 [0.123, 0.487]**
Combined vs. cognitive 9 11 −0.008 [-0.201, 0.186]
Combined vs. physical 9 12 0.08 [-0.102, 0.264]
Speed 0.00 (1.312e-08) 0.104 (54.037)*** F(2, 88) = 3.481,
p =0.035
148.492** Combined vs. control 15 47 0.308 [0.129, 0.486]***
Combined vs. cognitive 9 19 0.046 [-0.163, 0.256]
Combined vs. physical 14 25 0.258 [0.069, 0.447]**
Global cognition 0.000 (1.211e-08) 0.153 (86.725)* F(2, 15) = 1.655,
p = 0.224
44.504*** Combined vs. control 8 10 0.525 [0.172, 0.877]**
Combined vs. cognitivea 1 1 NA
Combined vs. physical 2 7 −0.048 [-0.621, 0.524]
Composite scores 0.052 (39.027) 0.019 (14.62) F(2, 6) = 2.884,
p = 0.133
16.743* Combined vs. control 5 4 0.392 [-0.017, 0.8]
Combined vs. cognitivea 3 3 NA
Combined vs. physicala 2 2 NA
Physical functions
Fitness 0.00 (2.848e-08) 0.059 (61.28)*** F(2, 62) = 1.917,
p = 0.156
176.29*** Combined vs. control 16 33 0.242 [0.075, 0.409]**
Combined vs. cognitive 8 18 0.338 [0.105, 0.571]**
Combined vs. physical 9 15 0.064 [-0.185, 0.313]
Balance 0.00 (2.757e-08) 0.026 (30.205)*** F(2, 92) = 0.192,
p = 0.826
130.952** Combined vs. control 17 58 0.273 [0.149, 0.396]***
Combined vs. cognitive 4 12 0.196 [-0.052, 0.444]
Combined vs. physical 9 25 0.229 [0.045, 0.413]*
Strength 0.037 (18.584) 0.092 (46.711) F(1, 27) = 0.266,
p < 0.768
71.739*** Combined vs. control 12 20 0.372 [0.103, 0.642]**
Combined vs. cognitive 3 5 0.463 [-0.081, 1.007]
Combined vs. physical 5 7 0.227 [-0.177, 0.632]
a

ES differences were only calculated for analyses with more than 3 ES.

#

Studies, Number of studies; #ES, Number of effect sizes; mean ES, mean Hedges' g; CI, Confidence interval; Level 2 variance, Variance in effect sizes within studies; Level 3 variance, Variance in effect sizes between studies; %, Proportion of the total variance of effect sizes attributed to this level; QE, test for heterogeneity in all effect sizes in the data set. Omnibus-test of all coefficients in the model (excluding the intercept).

*

p < 0.05;

**

p < 0.01;

***

p < 0.001.