Figure 3.

Patient-reported improvement of primary symptom (chronic pain). (A) Percentage of patients reporting any degree of improvement (yes/no) in their primary symptom (p < 0.001). (B) Participants' responses (N = 2,112) to the 11-point Single Assessment Numeric Evaluation (SANE), rating their current illness score in relation to their pre-treatment baseline, with zero being “no improvement” and 100 being “total improvement of primary symptom”. (C) Reported degree of improvement by age group (young adult <65 vs. elderly >65) of patients prescribed with FM-002 (n = 856) and FM-003 (n = 1,241). To facilitate visual interpretation, responses to the SANE were clustered into four groups by increasing degree of improvement: residual (0–10), slight (20–40), moderate (50–70), and robust (80–100). Participants prescribed with FM-001 and FM-004 were marginal (<1%) and responses were not included in the analysis to avoid confusion.