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. 2022 Mar 24;13:857930. doi: 10.3389/fendo.2022.857930

Table 1.

General Characteristics of included studies for association of NWO with CMRFs.

Author Year Country sample size Mean Age/Age Range Study Population Definition of NWO* Q.A
Total M F NWNO NWO
Bellissimo 2019 (15) USA 289 63 116 26 43 47 Adults/general population BF: 23% men, 30% women 6
Berg 2015 (16) Sweden 1471 581 890 1080 266 25-74 Adults /general population BF: 25% men , 38% women 8
W. K. Cho 2015 (17) Korea 1700 888 812 1266 144 13-18 Adolescents upper highest quartile (Q4) of age and sex specific Waist-to-height ratio 8
M. Correa 2020 (18) Colombia 1354 528 826 961 393 18-32 Adults /general population BF: 25.5% men , 38.9% women 9
Ramsaran 2017 (19) West Indies 236 76 160 189 74 18-32 Adults /general population BF: 23% men , 33% women 6
A. García 2020 (20) Colombia 1919 955 964 1035 884 13 Children and Adolescents BF: boys > 23.4%–28.3% and girls > 31.0%–34.1% 7
H. He 2019 (21) China 2654 (–) (-) 1916 729 46.9 ± 1380 Adults /general population BF: 21.4% men , 31.4% women 9
A. Jia 2018 (22) China 15291 1492 13799 9988 1771 under 75 Adults / general population BF: ≥24% for men and ≥33% for women 10
Kapoor 2020 (23) India 1147 619 528 200 364 47.3 ± 7.5 Adults /general population BF: , ≥20.6% men, ≥33.4% women, 9
Kim 2014 (24) Korea 12217 5313 6904 3382 1575 44 Adults /general population BF: ≥20.6% men, ≥33.4% women 8
Kim 2018 (25) Korea 3949 (–) (-) 2213 868 (-) Adults /general population BF: ≥23.1% men, ≥33.1% women 6
Sohee Kim 2015 (26) Korea 2078 1141 937 1795 283 53.4 Adults /general population BF: ≥25.4 % men, ≥31.4 % women 8
H. Zhao 2012 (27) China 407 (-) (-) (-) (-) (-) (-) BF: ≥25 % men, ≥35 % women 5
Tayefi 2019 (28) Iran 2439 (–) (-) 1311 1128 47 Adults /general population BF: > 25%men, >30% women 9
T. Shirasawa 2019 (8) Japan 117163 82487 34676 43055 12877 40-64 Adults /general population Waist-to-height ratio ≥ 0.5 10
A. Romero 2010 (6) USA 4116 2089 2027 2054 2062 41.3 Adults /general population BF: ≥23.1 % men, ≥33.3 % women 8
A. S. Olafsdottir 2016 (29) Iceland 182 96 86 106 76 17.7-18.9 High-school students/ adolescents BF: > 17.6% men , >31.6% women 5
F. M. Moy 2015 (30) Malaysia 858 0 858 511 237 40.47 ± 8.9 Adults /teachers BF: >28.52% 6
K. E. Martinez 2017 (31) USA 3600 (-) (-) 1624 288 adults Adults /general population BF: 27.8 ± 0.2% men, 40.5 ± 0.2 % women 5
P. Marques-Vidal 2010 (32) Switzerland 2301 0 2301 1667 173 35-75 Adults/general population whites BF: ≥38% 7
F. B. Madeira 2013 2013 (4) Brazil 1222 546 676 1111 111 23-25 young adults BF: ≥23% men, ≥30% women 10
P. J. Liu 2017 (33) China 412 0 412 214 198 55.72 Post menopause general population women third tertile of normal weight body fat 6
C. C. N. Da Silva 2021 (34) Brazil 787 346 441 553 47 23-25 Young adults >90th percentile body fat 10

CMRFs, cardio-metabolic risk factors; M,male; F, female; NWNO, normal weight none obese; NWO, normal weight obese; BF, body fat (based on percentage); USA, United State; Q.A, quality assessment based on the Newcastle Ottawa scale (out of 10 points); * all NWOs had BMIs within normal range.