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. 2022 Mar 24;10:808212. doi: 10.3389/fcell.2022.808212

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Copyright © 2022 Zhang, Wang, Yuan, Wu, Xu, Chen, Zhang and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ITGAL expression correlated with monocyte, macrophages, and T cell exhaustion in stomach adenocarcinoma (STAD). Markers include CD86 and CSF1R of monocytes; CCL2, CD68, and IL10 of TAMs; NOS2, IRF5, and PTGS2 of M1 macrophages; and CD163, VSIG4, and MS4A4A of M2 macrophages. Scatterplots of correlations between ITGAL expression and gene markers of monocytes (A), TAMs (B), and M1 (C), M2 macrophages (D) and T-cell exhaustion (E) in STAD (n = 415).