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. 2022 Mar 24;9:797116. doi: 10.3389/fcvm.2022.797116

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Copyright © 2022 Torzewski.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Abundant CRP expression in the lung after SARS-CoV-2 infection. Representative immunohistochemistry of paraffin embedded lung tissue from a patient died of COVID-19. Diffuse alveolar damage with intensive positive CRP staining (monoclonal antibody (mAb) clone CRP-8, Sigma) of macrophages as identified with mAb against CD68 (clone PG-M1, Dako) (A,C). Negative control with an irrelevant isotype-matched mAb (FLEX, Dako) (B). Interstitial pulmonary fibrosis illustrated by Elastica-van Gieson stain (D).