Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 24;13:866170. doi: 10.3389/fendo.2022.866170

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Mindler, Stauffer, Kranzl, Penzkofer, Ganger, Radler, Haeusler and Raimann

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Lower limb deformity in a 7-year-old girl (case 3) undergoing Burosumab therapy. Full long leg standing radiographs and lower limb deformity analysis were obtained prior (A) to initiation, as well as during follow-up appointments. Valgus deformity was observed and a temporary hemiepiphysiodesis procedure performed in both legs (x-ray 2 months postoperative) despite persistent rachitic status (B). Normalization of MAD in one leg occurred sooner (C). As a sign of valgus deformity rebound, a mild recurrence of lateralization of the MAD after successful guided growth surgery despite Burosumab therapy was observed at the last follow-up 12 months after plate removal (D).