Table 5.
Prediction of MHC-II epitopes from CEA by four different servers
| Server | Start position | Sequences | Rank |
|---|---|---|---|
| Rankpep | Scorea | ||
| 15 | WQRLLLTAS | 12.274 | |
| 81 | GYVIGTQQA | 9.862 | |
| 546 | RLQLSNGNR | 9.103 | |
| 453 | GNIQQHTQE | 6.885 | |
| MHCpred | Predicted IC50 value (nM)b | ||
| 691 | IMIGVLVGV | 16.18 | |
| 519 | VAFTCEPEA | 22.23 | |
| 341 | VALTCEPEI | 26.67 | |
| 589 | VLYGPDTPI | 29.51 | |
| MHC2pred | Scorec | ||
| 533 | LWWVNGQSL | 1.587 | |
| 688 | TVGIMIGVL | 1.453 | |
| 75 | GNRQIIGYV | 1.425 | |
| 467 | ITEKNSGLY | 1.424 | |
| IEDB | Percentile rankd | ||
| 12 | CIPWQRLLLTASLLT | 0.91 | |
| 27 | ATVGIMIGVLVGVAL | 4.20 | |
| 37 | GREIIYPNASLLIQN | 11.00 |
aHigh score¼good binder; blow predicted IC50 value¼good binder; chigh score = good binder; dlow percentile rank = good binder