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. 2022 Mar 24;10:859406. doi: 10.3389/fchem.2022.859406

TABLE 1.

Crosslinking agents used in the preparation of different categories of CDNSs.

CDNSs classes Crosslinkers
Carbonate Carbonyls: diphenyl carbonate (DPC); 1,1′-carbonyl diimidazole (CDI); dimethyl carbonate (DMC) and triphosgene
Carbamate Diisocyanates: 1,6-hexamethylene diisocyanate (HDI); methylene diphenyl diisocyanate (MDI) Appell et al. (2018); toluene 2,4-diisocyanate (TDI) and toluene 2,6-diisocyanate Krabicová et al. (2020)
Ester Dianhydrides: pyromellitic dianhydride (PMA); ethylenediaminetetraacetic acid dianhydride (EDTA) Ferro et al. (2017); Epiclon-B-4400 Gholibegloo et al. (2019a); dialcohol 2-hydroxyethyl disulfide (2-HEDS) can be use together with PMA to introduce disulfide bonds Trotta et al. (2016b)
Carboxylic acids: citric acid (CA) Rubin Pedrazzo et al. (2019) and 2,6-naphthalene dicarboxylic acid (NDCA) Nait Bachir et al. (2019)
Ether Epoxides: epichlorohydrin; 1,4-butanediol diglycidylether (BDE) Rizzi et al. (2021); E-51 epoxy resin Lai et al. (2012)
Polyamidoamine 2,2′-bis(acrylamido)acetic acid and its polyamidoamine derivates (PAA) formed by reaction with amines (such as 2-methylpiperazine) Swaminathan et al. (2010a)
Polyamine Polyamines: 1,6-hexanediamine (am6), 1,8-octanediamine, 1,12-dodecanediamine (am12) Russo et al. (2016); Utzeri et al. (2022)
Other linkers Dichloromethane Noothi et al. (2020) and N,N′-methylene bisacrylamide (MBA) Pawar et al. (2019)