Table 2.
Data of the five women with known viral load at delivery
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | |
|---|---|---|---|---|---|
| Mother | |||||
| Age (years) | 27 | 33 | 26 | 34 | 35 |
| Timing of HIV diagnosis | Delivery | 3rd trimester | Pregestational | Delivery | Pregestational |
| CD4 count in third trimester (cel/µl) | 200–300 | 200–300 | > 750 | < 200 | < 200 |
| Viral load at childbirth (copies/ml) | 10,000–100,000 | 10,000–100,000 | < 50 | > 100,000 | < 50 |
| Gestational age at birth (weeks) | 37 | 37 | 37 | 37 | 38 |
| Type of delivery | Vaginal | CS | CS | CS | CS |
| ART before pregnancy | No | No | No | No |
Yes (ZDV + 3TC + EFV) |
| ARV prophylaxis at delivery | No | n/d | n/d | n/d | ZDV iv |
| Child | |||||
| Birth weight (grams) | 2000–4000 | 2000–4000 | 2000–4000 | 2000–4000 | 2000–4000 |
| Type of ARV prophylaxis in the newborn |
ZDV + 3TC + RTG |
ZDV + 3TC | 3TC | n/d | ZDV |
| Maternal breastfeeding | No | No | No | n/d | n/d |
| Age at diagnosis (months) | 0.5 | 2 | 3 | 10 | 59 |
| Viral load at diagnosis (copies/ml) | 10,000–100,000 | 10,000–100,000 | 10,000–100,000 | > 100,000 | > 100,000 |
| CD4 count at diagnosis (cel/µl) | > 750 | > 750 | > 750 | > 750 | > 750 |
| CDC clinical classification of HIV at diagnosis | B | N | A | A | C |
HIV human immunodeficiency virus, CS cesarean section, ART antiretroviral therapy, ZDV zidovudine, 3TC lamivudine, EFV efavirenz, ARV antiretroviral prophylaxis, n/d no data available, RTG raltegravir, CDC Centers for Diseases Control and Prevention