TABLE 3.
Odds ratios (95% confidence intervals) of the dates of statin prescription (1 year) for the exacerbation of COPD.
Characteristics | Odds ratios for aggravated COPD |
|||
Model 1† | P-value | Model 2‡ | P-value | |
COPD participants (n = 26,875) | ||||
Statin prescription (1 year) | 0.74 (0.69–0.78) | <0.001* | 0.79 (0.74–0.85) | <0.001* |
Age < 60 years old (n = 6,115) | ||||
Statin prescription (1 year) | 0.79 (0.64–0.96) | 0.020* | 0.76 (0.61–0.96) | 0.018* |
Age ≥ 60 years old (n = 20,760) | ||||
Statin prescription (1 year) | 0.74 (0.69–0.78) | <0.001* | 0.80 (0.74–0.85) | <0.001* |
Males (n = 15,126) | ||||
Statin prescription (1 year) | 0.75 (0.69–0.80) | <0.001* | 0.83 (0.76–0.90) | <0.001* |
Females (n = 11,749) | ||||
Statin prescription (1 year) | 0.72 (0.65–0.80) | <0.001* | 0.72 (0.65–0.81) | <0.001* |
Low income (n = 13,081) | ||||
Statin prescription (1 year) | 0.71 (0.65–0.78) | <0.001* | 0.78 (0.71–0.86) | <0.001* |
High income (n = 13,794) | ||||
Statin prescription (1 year) | 0.64 (0.58–0.71) | <0.001* | 0.80 (0.73–0.87) | <0.001* |
Urban (n = 9,982) | ||||
Statin prescription (1 year) | 0.72 (0.65–0.80) | <0.001* | 0.76 (0.68–0.85) | <0.001* |
Rural (n = 16,893) | ||||
Statin prescription (1 year) | 0.75 (0.69–0.80) | <0.001* | 0.81 (0.75–0.88) | <0.001* |
CCI, Charlson comorbidity index; COPD, chronic obstructive pulmonary disease; DBP, diastolic blood pressure; SBP, systolic blood pressure.
*Unconditional logistic regression, significance at P < 0.05.
†Model 1 was adjusted for age, sex, income, and region of residence.
‡Model 2 was adjusted as model 1 plus total cholesterol, SBP, DBP, fasting blood glucose, obesity, smoking, alcohol consumption, history of dyslipidemia, history of asthma, and CCI scores.