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. 2022 Mar 24;9:842948. doi: 10.3389/fmed.2022.842948

TABLE 3.

Odds ratios (95% confidence intervals) of the dates of statin prescription (1 year) for the exacerbation of COPD.

Characteristics Odds ratios for aggravated COPD
Model 1 P-value Model 2 P-value
COPD participants (n = 26,875)
  Statin prescription (1 year) 0.74 (0.69–0.78) <0.001* 0.79 (0.74–0.85) <0.001*
Age < 60 years old (n = 6,115)
  Statin prescription (1 year) 0.79 (0.64–0.96) 0.020* 0.76 (0.61–0.96) 0.018*
Age ≥ 60 years old (n = 20,760)
  Statin prescription (1 year) 0.74 (0.69–0.78) <0.001* 0.80 (0.74–0.85) <0.001*
Males (n = 15,126)
  Statin prescription (1 year) 0.75 (0.69–0.80) <0.001* 0.83 (0.76–0.90) <0.001*
Females (n = 11,749)
  Statin prescription (1 year) 0.72 (0.65–0.80) <0.001* 0.72 (0.65–0.81) <0.001*
Low income (n = 13,081)
  Statin prescription (1 year) 0.71 (0.65–0.78) <0.001* 0.78 (0.71–0.86) <0.001*
High income (n = 13,794)
  Statin prescription (1 year) 0.64 (0.58–0.71) <0.001* 0.80 (0.73–0.87) <0.001*
Urban (n = 9,982)
  Statin prescription (1 year) 0.72 (0.65–0.80) <0.001* 0.76 (0.68–0.85) <0.001*
Rural (n = 16,893)
  Statin prescription (1 year) 0.75 (0.69–0.80) <0.001* 0.81 (0.75–0.88) <0.001*

CCI, Charlson comorbidity index; COPD, chronic obstructive pulmonary disease; DBP, diastolic blood pressure; SBP, systolic blood pressure.

*Unconditional logistic regression, significance at P < 0.05.

Model 1 was adjusted for age, sex, income, and region of residence.

Model 2 was adjusted as model 1 plus total cholesterol, SBP, DBP, fasting blood glucose, obesity, smoking, alcohol consumption, history of dyslipidemia, history of asthma, and CCI scores.