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. 2021 Nov 24;46(2):327–336. doi: 10.4093/dmj.2021.0046

Table 3.

Subgroup analysis of study participants

Variable Continuity of physical activity
P value for interaction
Continuously physically inactive Physically active to inactive Physically inactive to active Continuously physically active
Age, yr 0.6837
 <65 1 (reference) 1.02 (0.78–1.33) 0.81 (0.63–1.04) 0.72 (0.51–1.02)
 ≥65 1 (reference) 0.87 (0.69–1.09) 0.79 (0.62–0.99) 0.84 (0.63–1.12)
Sex 0.0216
 Male 1 (reference) 1.10 (0.89–1.36) 0.81 (0.66–1.01) 0.70 (0.53–0.92)
 Female 1 (reference) 0.68 (0.50–0.92) 0.76 (0.58–1.00) 1.001 (0.70–1.44)
Hypertension 0.6907
 No 1 (reference) 0.79 (0.53–1.16) 0.73 (0.52–1.03) 0.86 (0.56–1.31)
 Yes 1 (reference) 0.96 (0.79–1.17) 0.81 (0.66–0.98) 0.75 (0.58–0.97)
Dyslipidemia 0.3024
 No 1 (reference) 0.77 (0.58–1.02) 0.70 (0.54–0.91) 0.76 (0.55–1.06)
 Yes 1 (reference) 1.05 (0.84–1.30) 0.86 (0.69–1.07) 0.79 (0.59–1.06)
CKD 0.6063
 No 1 (reference) 0.93 (0.77–1.12) 0.78 (0.65–0.94) 0.73 (0.57–0.93)
 Yes 1 (reference) 0.85 (0.54–1.33) 0.80 (0.52–1.24) 1.06 (0.63–1.78)
CVD 0.6556
 No 1 (reference) 0.94 (0.78–1.12) 0.77 (0.65–0.92) 0.77 (0.61–0.96)
 Yes 1 (reference) 0.74 (0.35–1.55) 1.02 (0.57–1.79) 0.99 (0.45–2.18)
Obesitya 0.5058
 No 1 (reference) 0.81 (0.62–1.05) 0.75 (0.59–0.96) 0.70 (0.50–0.96)
 Yes 1 (reference) 1.04 (0.83–1.31) 0.83 (0.66–1.04) 0.87 (0.65–1.18)
Weight changeb 0.4933
 Gain 1 (reference) 0.96 (0.67–1.39) 1.03 (0.75–1.41) 0.73 (0.45–1.19)
 Stable 1 (reference) 0.96 (0.78–1.18) 0.72 (0.58–0.89) 0.79 (0.60–1.02)
 Loss 1 (reference) 0.70 (0.39–1.24) 0.68 (0.40–1.15) 0.87 (0.45–1.67)
Malignancy 0.1431
 No 1 (reference) 0.90 (0.75–1.07) 0.79 (0.66–0.93) 0.74 (0.59–0.93)
 Yes 1 (reference) 1.39 (0.70–2.73) 0.85 (0.40–1.84) 1.47 (0.70–3.08)

Adjusted for age, sex, current smoking, alcohol, income, waist circumference, hypertension, dyslipidemia, CKD, stroke, myocardial infarction, and fasting blood glucose.

CKD, chronic kidney disease; CVD, cardiovascular disease.

a

The body mass index cutoff of 25 kg/m2 was used to define obesity in the Korean population in this study,

b

Weight change was calculated for each subject as the difference in weight between the follow-up health examination and baseline examination and divided into three categories: stable, gain or loss of less than 5% of body weight at baseline; gain, gain of 5% or more of body weight at baseline; loss, loss of 5% or more of body weight at baseline.