Table 3.

Remission rates of T2DM after intensive insulin therapy in newly diagnosed patients as confirmed by randomized clinical trials

	Patients	Type	Number	Follow-up	End-point	Outcome
Ilkova et al. [50]	Newly diagnosed T2DM	CSII for 2 weeks	13	6 months	FPG <7.8 mmol/L or PPG <10.0 mmol/L	69%
Li et al. [51]	Newly diagnosed T2DM	CSII for 2 weeks	138	2-year	FPG <7.0 mmol/L or PPG <10.0 mmol/L	42%
Weng et al. [52]	Newly diagnosed T2DM	CSII vs. MDI vs. OHA for 2 weeks	124 vs. 113 vs. 94	1-year	FPG <6.1 mmol/L or PPG < 8.0 mmol/L	51% vs. 45% vs. 27%
Chen et al. [53]	Newly diagnosed T2DM	CSII for 2 weeks	118	1-year	FPG <7.0 mmol/L or PPG <10.0 mmol/L	55%
Chon et al. [54]	Newly diagnosed T2DM	MDI vs. OHA for 12 weeks	50 vs. 47	2-year	HbA1c <7%	47% vs. 23%

T2DM, type 2 diabetes mellitus; CSII, continuous subcutaneous insulin infusion; FPG, fasting plasma glucose; PPG, postprandial plasma glucose; MDI, multiple daily insulin injection; OHA, oral hypoglycemic agent; HbA1c, glycosylated hemoglobin.