Table 3.
Association between comorbidity (and age) and 30-day mortality
| Comorbidity | N | 30-day mortality | OR (95% CI) 30-day mortality | 1-year mortality | OR (95% CI) 1 year mortality | ||
| Univariable | Multivariable | Univariable | Multivariable | ||||
| Diabetes mellitus: | |||||||
| Uncomplicated | 200 (19.2) | 24 (12.0) | 1.23(0.74 to 1.96) | 1.09(0.65 to 1.79) | 53 (26.5) | 0.92(0.64 to 1.30) | 0.88(0.60 to 1.28) |
| End-organ damage | 13 (1.3) | 6 (46.2) | 7.76(2.46 to 23.8)* | 9.28(2.40 to 3.73)* | 11 (84.6) | 14.8(3.92 to 96.0)* | 14.0(3.42 to 95.0)* |
| Liver disease: | |||||||
| Mild | 140 (13.5) | 7 (5.0) | 0.42(0.18 to 0.85) | 0.46(0.19 to 0.96) | 40 (28.6) | 1.04(0.70 to 1.54) | 0.95(0.61 to 1.46) |
| Moderate to severe | 9 (0.9) | 1 (11.1) | 1.08(0.06 to 5.96) | 0.39(0.01 to 4.45) | 4 (44.4) | 2.09(0.51 to 7.96) | 1.47(0.19 to 8.10) |
| Malignancy: | |||||||
| Leukaemia, lymphoma, solid | 181 (17.4) | 14 (7.7) | 0.68(0.36 to 1.19) | 0.71(0.36 to 1.28) | 57 (31.5) | 1.24(0.87 to 1.75) | 1.64(1.11 to 2.40) |
| Metastatic solid tumour | 133 (12.8) | 24 (18.0) | 2.15(1.29 to 3.49)* | 2.06(1.18 to 3.54) | 85 (63.9) | 6.09(4.16 to 9.02)* | 6.93(4.56 to 10.6)* |
| AIDS | 3 (0.3) | 0 (0.0) | ∞ | ∞ | 2 (66.7) | ∞ | ∞ |
| Chronic kidney disease | 169 (16.3) | 11 (6.5) | 0.55(0.28 to 1.02) | 0.47(0.22 to 0.93) | 37 (21.9) | 0.69(0.46 to 1.01) | 0.75(0.48 to 1.16) |
| Congestive heart failure | 133 (12.8) | 17 (12.8) | 1.31(0.73 to 2.23) | 1.08(0.57 to 1.94) | 35 (26.3) | 0.92(0.60 to 1.37) | 0.92(0.57 to 1.46) |
| Myocardial infarction | 139 (13.4) | 17 (12.2) | 1.24(0.69 to 2.10) | 1.02(0.54 to 1.84) | 40 (28.8) | 1.06(0.71 to 1.56) | 1.06(0.67 to 1.66) |
| Chronic pulmonary disease | 134 (12.9) | 22 (16.4) | 1.87(1.10 to 3.06) | 1.87(1.07 to 3.18) | 41 (30.6) | 1.17(0.78 to 1.72) | 1.31(0.85 to 2.00) |
| Peripheral vascular disease | 121 (11.6) | 12 (9.9) | 0.94(0.48 to 1.71) | 0.63(0.30 to 1.21) | 35 (28.9) | 1.06(0.69 to 1.60) | 0.90(0.55 to 1.43) |
| CVA or TIA | 141 (13.6) | 23 (16.3) | 1.86(1.11 to 3.03) | 1.44(0.82 to 2.45) | 50 (35.5) | 1.52(1.04 to 2.20) | 1.51(0.99 to 2.29) |
| Dementia | 36 (3.5) | 8 (22.2) | 2.58(1.07 to 5.57) | 1.32(0.52 3.01) | 12 (33.3) | 1.31(0.63 to 2.61) | 0.93(0.41 to 1.99) |
| Hemiplegia | 3 (0.3) | 0 (0.0) | ∞ | ∞ | 0 (0.0) | ∞ | ∞ |
| Connective tissue disease | 77 (7.4) | 9 (11.7) | 1.15(0.52 to 2.27) | 1.07(0.48 2.22) | 18 (23.4) | 0.78(0.44 to 1.32) | 0.99(0.54 to 1.74) |
| Peptic ulcer disease | 25 (2.4) | 3 (12.0) | 1.18(0.28 to 3.48) | 0.89(0.18 to 3.06) | 9 (36.0) | 1.47(0.62 to 3.31) | 1.35(0.50 to 3.35) |
| Age, per decade | 10.5(10.3 to 10.7)* | 10.4(10.2 to 10.6)* | 10.3(10.2 to 10.4)* | 10.3(10.2 to 10.4)* | |||
Data are presented as number (percentage) of patients and as ORs with 95% CIs.
*Statistically significant after Bonferroni correction (p<0.003).
CVA, cerebrovascular accident; TIA, transient ischaemic attack.