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. 2022 Apr 5;12(4):e057196. doi: 10.1136/bmjopen-2021-057196

Table 4.

Validation of the CCI and comparison with the news

AUC (95% CI)
30-day mortality 1-year mortality
CCIoriginal* 0.643(0.589;0.697) 0.696(0.660;0.732)†
Age‡ 0.661(0.609 to 0.712) 0.616(0.581 to 0.652)
Comorbidities 0.568(0.507 to 0.628) 0.663(0.625 to 0.701)
NEWS 0.706(0.656 to 0.756) 0.594(0.555 to 0.632)
NEWS and CCIoriginal 0.743(0.697 to 0.789) 0.696(0.662 to 0.730)
NEWS and age‡ 0.740(0.695 to 0.785) 0.623(0.587 to 0.660)
NEWS and comorbidities 0.719(0.669 to 0.769) 0.681(0.645 to 0.716)

*The AUC of the original CCI was comparable to the AUC of the updated CCI, that is, 0.642 (0.588 to 0.696) for 30-day mortality and 0.695 (0.659 to 0.732) for 1-year mortality.

†When excluding short-term deaths, the AUC of the CCI increased to 0.703.

‡Age, per decade from 50 years.

AUC, area under receiver operator curve; CCI, Charlson Comorbidity Index; NEWS, National Early Warning Score.