Table 4.
Validation of the CCI and comparison with the news
AUC (95% CI) | ||
30-day mortality | 1-year mortality | |
CCIoriginal* | 0.643(0.589;0.697) | 0.696(0.660;0.732)† |
Age‡ | 0.661(0.609 to 0.712) | 0.616(0.581 to 0.652) |
Comorbidities | 0.568(0.507 to 0.628) | 0.663(0.625 to 0.701) |
NEWS | 0.706(0.656 to 0.756) | 0.594(0.555 to 0.632) |
NEWS and CCIoriginal | 0.743(0.697 to 0.789) | 0.696(0.662 to 0.730) |
NEWS and age‡ | 0.740(0.695 to 0.785) | 0.623(0.587 to 0.660) |
NEWS and comorbidities | 0.719(0.669 to 0.769) | 0.681(0.645 to 0.716) |
*The AUC of the original CCI was comparable to the AUC of the updated CCI, that is, 0.642 (0.588 to 0.696) for 30-day mortality and 0.695 (0.659 to 0.732) for 1-year mortality.
†When excluding short-term deaths, the AUC of the CCI increased to 0.703.
‡Age, per decade from 50 years.
AUC, area under receiver operator curve; CCI, Charlson Comorbidity Index; NEWS, National Early Warning Score.