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. 2022 Apr 6;12(4):e054347. doi: 10.1136/bmjopen-2021-054347

Table 1.

Subject demographics and clinical features

NC SCD aMCI AD P value
N 148 138 74 43
Sex (M/F) 65/83 38/100 31/43 17/26 0.001
Age, years 64.85±7.22 64.66±7.02 68.07±7.96 70.43±9.36 <0.001
Years of education 12.67±3.36 12.84±3.05 11.19±4.12 10.24±4.28 <0.001
MMSE Score 29.00 (28.00, 30.00) 29.00 (28.00, 30.00) 26.00 (24.00, 28.00) 18.50 (13.75, 21.00) <0.001
MoCA-B Score 26.00 (24.00, 28.00) 26.00 (24.00, 27.00) 21.00 (19.00, 23.00) 14.00 (11.00, 16.00) <0.001

Age and years of education are presented as mean±SD, MMSE and MoCA-B Scores are presented as median (IQR). χ2 test was used for categorical variables and Tukey’s or Dunn’s test for continuous variables.

AD, Alzheimer’s disease; aMCI, amnestic mild cognitive impairment; MMSE score, Mini-Mental State Examination score; MoCA-B score, Montreal Cognitive Assessment-Basic score; NC, normal controls; SCD, subjective cognitive decline.