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. 2022 Mar;10(5):241. doi: 10.21037/atm-21-4402

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2022 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Development of a 10-pMRlncRNA risk signature for prognosis prediction. (A) Validation of the candidate pMRlncRNAs using LASSO regression analysis. (B) Explanation for LASSO coefficient profile plot of prognostic pMRlncRNAs. (C) Patients with melanoma patients sorted by growing risk score in TCGA cohort. (D) Survival status of patients with melanoma in TCGA cohort. (E) Heatmap showing the expression levels of 10 pMRlncRNA in the 2 risk groups from TCGA cohort. (F) Survival analysis performed for the 10-pMRlncRNA risk signature to assess overall survival in TCGA cohort. (G-J) Validation of the above results in the GSE65904 cohort. pMRlncRNAs, potential-N6-methyladenosine-related long noncoding RNAs; LASSO, least absolute shrinkage and selection operator; TCGA, The Cancer Genome Atlas.